Reye's syndrome: children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: aspirin may cause a severe allergic reaction which may include hives, facial swelling, asthma (wheezing), shock. Stomach bleeding this product contains a nonsteroidal anti-inflammatory drug (NSAID), which may cause stomach bleeding. The chance is higher if you are age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinner (anticoagulant) or steroid drug, take other drugs containing an NSAID (aspirin, ibuprofen, naproxen, or others), have 3 or more alcoholic drinks every day while using this product, take more or for a longer time than directed. Do not use if you have ever had an allergic reaction to any other pain reliever/ fever reducer. Ask a doctor before use if you have asthma, ulcers, bleeding problems, stomach problems that last or come back, such as heartburn, upset stomach, or stomach pain, high blood pressure, heart or kidney disease, taken a diuretic, reached age 60 or older. Ask a doctor or pharmacist before use if you are taking any other drug containing an NSAID (prescription or nonprescription), taking a blood thinning (anticoagulant) or steroid drug, taking a prescription drug for diabetes, gout, or arthritis. Stop use and ask a doctor if an allergic reaction occurs (seek medical help right away), new symptoms occur, you feel faint, vomit blood, or have bloody or black stools (these are signs of stomach bleeding), stomach pain or upset gets worse or lasts, ringing in the ears or loss of hearing occurs, painful area is red or swollen, pain gets worse or lasts more than 10 days, fever gets worse or lasts more than 3 days. Caffeine the recommended does of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness and, occasionally, rapid heart beat. If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. Overdose in case of overdose, get medical help or contact a poison control center right away. Do not use if seal under bottle cap imprinted with sealed for your protection is broken or missing.