Liver this product contains acetaminophen. Severe liver damage may occur if your child takes more than 5 doses in 24 hours, which is the maximum daily amount; with other drugs containing acetaminophen. Sore throat if sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use: with any other drug containing acetaminophen (prescription or non prescription ) (if you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist); to make a child sleepy; with any other drug containing diphenhydramine, even one used on the skin; in a child who is taking a prescription monoamine oxidase inhibitor (maoi) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the maoi drug (if you do not know if your child’s prescription drug contains an maoi, ask a doctor or pharmacist before giving this product). Ask a doctor before use if your child has liver disease; heart disease; diabetes; high blood pressure; thyroid disease; glaucoma; a breathing problem such as chronic bronchitis; persistent or chronic cough such as occurs with asthma; cough that occurs with too much phlegm (mucus). Ask a doctor or pharmacist before use if your child is taking the blood thinning drug warfarin; taking sedatives or tranquilizers. When using this product: do not use more than directed; excitability may occur, especially in children; marked drowsiness may occur; sedatives and tranquilizers may increase drowsiness. Stop use and ask a doctor if: nervousness, dizziness, or sleeplessness occur; pain, nasal congestion, or cough gets worse or lasts more than 5 days; fever gets worse, or lasts more than 3 days; redness or swelling is present; new symptoms occur; cough comes back, or occurs with fever, rash, or headache that lasts (these could be signs of a serious condition). Keep out of reach of children. Overdose taking more than the recommended dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a poison control center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms. Other tamper evident: do not use if neckband on bottle cap is broken or missing.