Item No. 0343977

Photo of Nature Made SAM-e Complete 400 mg. Tablets Value Size - 36 ct

Nature Made SAM-e Complete Enteric Coated Tablets, 400mg - 36 ct

Price: $39.99

Member Savings (17% Off)

Was $47.99

Availability: Usually ships in 1 business day


New look, same product. SAM-e is a naturally occurring molecule made in the cells of our bodies. However, SAM-e levels can run low due to various factors such as diet and aging. Nature Made SAM-e Complete can help to replenish your SAM-e levels and restore your healthy mood when taken daily. If you are new to SAM-e, Nature Made SAM-e Complete 400 mg is a great place to start. Nature Made SAM-e also helps support joint comfort, which may naturally deteriorate with physical activity and age. SAM-e provides a source of sulfur, which is a critical component of joint tissue.

  • For a limited time, you may receive either bottle while we update our packaging. Both have the same great product inside. Based on new FDA regulations, you may also notice a change in the unit of measure and/or daily value for certain products.
  • Contains up to a 36-day supply of Nature Made SAM-e Complete 400 mg tablets, 36 tablets per container.
  • Naturally supports a healthy mood and emotional well-being. Helps support joint comfort. Helps support a healthy mood in as little as 714 days when taken daily.
  • Adults, start by taking 1 tablet daily with water on an empty stomach. If benefits are not achieved within two weeks, you may require a higher level of supplementation.
  • Guaranteed to meet our high quality standards. Made from carefully selected ingredients under strict manufacturing processes. No artificial flavors, no preservatives, gluten free.
Nature Made SAM-e Complete Enteric Coated Tablets, 400mg - 36 ct is rated 4.9 out of 5 by 9.
Rated 5 out of 5 by from Goodbye back pain! Since the birth of my 3rd child I have had sharp back pain if I slept on my stomach- four years later the pain gets so bad I would need help to roll over and sit up in bed! I did not want to take pain killer on a regular basis. I stay in shape and increased yoga but the pain did not go away. Until now my only solution was not to sleep on my stomach- hard to control when I am asleep! For years my sister told me to try the SAM-E, but the price was a deterrent. I saw it on a great promotion on Rite and decided it was worth a try- I should have stocked up!! After 2 weeks of the SAM-E once a day, I have no pain and can sleep on my stomach again!! Thank you!!!
Date published: 2016-08-15
Rated 5 out of 5 by from My daily dose of sanity I am turning 62 years old this month. I have been in public education for 25 years. Nothing has come close to helping me maintain my sense of humor and staying calm in times of elevated stress than Nature Made Sam-e. I did research some years ago when I started to feel my stress level elevating. I was working full time and taking care of my elderly father. Sam-e has been used in Europe for years for mild depression. I decided to try it. It worked beautifully. I was able to not sweat the small stuff and get on with living a balanced life. I have recommended it to family members and friends. I would recommend it to anyone who needs a little help balancing and who does not want to have chemicals or prescriptions in their body.
Date published: 2016-11-01
Rated 5 out of 5 by from I Never Let Myself Run Out of This Supplement! After researching SAM-e, I decided to try it. I didn't see an improvement in my joint comfort, but the claims of improving emotions and mood are absolutely true for me. I feel more calm and able to handle the stresses of my busy and sometimes difficult life when I take it. I didn't refill once for a period of time, and that was a mistake. SAM-e will be a permanent part of my supplement routine from now on.
Date published: 2016-08-26
Rated 5 out of 5 by from SAM-e 400 mg SAM-e 400 mg helps me in the most stressful work situations. I spoke to my doctor and he also recommends it as a compliment to my low blood pressure pills, and other patients also take them. The SAM-e especially for women that multi-task either in the home or on a job will calm the inner emotions to help in any situation. Thank you.
Date published: 2016-12-26
Rated 5 out of 5 by from I AM GRATEFUL FOR NATURE MADE SAM-e Complete! A close friend who works in dog rescue recommended that I try giving my dog, who has had just so many behavioral and medical issues her entire life, a trial on Sam-e and so I did. She seems so much more normal. It IS expensive but it's worth it to me to have my dog who is ,after all, a member of my family feeling and acting better.
Date published: 2017-10-29
Rated 4 out of 5 by from It does help I tried this and did not feel results initially. It took about 2 weeks to notice a difference in how I felt. After 3 weeks I am feeling much better. I am more motivated and positive, so I am glad that I went with something more natural than a prescription drug.
Date published: 2018-01-12
Rated 5 out of 5 by from Help balance hormones/ mood Seems to be working for me. It definitely helps in improving my mood and outlook on life. I feel more balanced.
Date published: 2019-08-20
Rated 5 out of 5 by from My daily go-to supplement. I have taken these for years and can tell the difference in my body if I run out.
Date published: 2017-03-26
  • y_2019, m_9, d_14, h_19
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasreviews, tv_1, tr_8
  • loc_en_US, sid_0343977, prod, sort_[SortEntry(order=RELEVANCE, direction=DESCENDING)]
  • clientName_riteaid
  • bvseo_sdk, p_sdk, 3.2.1
  • CLOUD, getContent, 55.27ms
Height 5.13 inches
Width 3.13 inches
Depth 2.25 inches
Product Weight 0.149375 oz
Strength 400 mg
Dosage 1 tablet(s)
Unit Price $111.08 per 100 Tablets (on regular retail)
Name Nature Made SAM-e Complete Enteric Coated Tablets, 400mg - 36 ct
Available Online
Package Count 36
Extended Size 36 tablets
Container Type bottle
Form Tablets
Strength 400
Strength UOM mg
Dosage 1
Dosage UOM tablet(s)
Model 1107Z
Indications Clinically proven for healthy mood & joint comfort naturally restores a healthy mood
Disclaimer Provides SAM-e which is produced and used by the body.Complete because studies have shown that SAM-e helps support a healthy mood and joint comfort.Based on U.S. News & World Report - Pharmacy Times Survey of pharmacists recommending this category.Thes
Country of Manufacture United States
Serving Size 1 Tablet
Nutritional/Supplemental Facts

Sam-e (s-adenosylmethionine) 400 mg, is or contains gluten free

Ingredient Preference Gluten Free
Allergy Option Yeast Free

Adults, start by taking 1 tablet daily with water on an empty stomach. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level for you, gradually increase the number of tablets (maximum 1600 mg/day) until benefits are achieved.Store tightly closed, in a cool, dry place, out of reach of children. Do not use if imprinted seal under cap is broken or missing.


SAM-e S-adenosylmethionine Tosylate Disulfate, Cellulose Gel, Methacrylic Acid Copolymer, Stearic Acid, Silicon Dioxide, Triethyl Citrate, Magnesium Stearate, Color Added, Mannitol, Sodium Starch Glycolate.


CAUTION: People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide should not take any product containing SAM-e except under a physician's supervision. If you are pregnant, nursing, or taking any medications including antidepressants, consult your physician before use.